Does the drug semaglutide have an effect on the style of meals?

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In latest studies, individuals have described unusual adjustments in how sure meals style or attraction to them when they’re taking semaglutide. Mascot/Getty Photos
  • Semaglutide is one such drug that’s obtainable for each the administration of kind 2 diabetes and for weight administration.
  • The drug is offered below the names Rybelsus, Ozempic, and Wegovy.
  • The drug has lately attracted the eye of many individuals on social media for its potential advantages.
  • There have additionally been latest anecdotal studies of drug use attributable to adjustments in the best way individuals style sure meals and drinks.
  • Specialists be aware that each one therapies carry a threat of negative effects.

Semaglutide is a drug that has been getting a whole lot of consideration lately in social media and within the information for its potential advantages and dangers, in addition to the latest lack of a producer.

The drug is marketed below the names Rebelsus and Ozempic for blood sugar administration in individuals with kind 2 diabetes. Rybelsus is an oral model of semaglutide {that a} affected person takes each day, whereas Ozempic is an injectable model that’s administered below the pores and skin as soon as every week.

A protracted-acting, injectable type of the drug can be offered below the identify Vegovi for weight administration in overweight or obese adults who’ve weight-related circumstances reminiscent of hypertension or excessive ldl cholesterol.

Endocrinologist at Lenox Hill Hospital in New York Dr. Carolyn Messer, MD, “A health care provider might prescribe semaglutide for a diabetic affected person who might profit from a potent blood sugar-lowering agent in addition to have to shed weight and scale back cardiovascular threat.” Metropolis, advised Healthline.

“Equally, a physician might prescribe this drug for a affected person who’s obese or overweight and might also be creating insulin resistance,” she mentioned.

Semaglutide is normally mixed with dietary changes and common train, typically with different medicines reminiscent of metformin.

Like every drugs, semaglutide carries a threat of attainable negative effects that have to be weighed towards the potential advantages. Some sufferers might expertise extra negative effects than others.

“The commonest side-effects are nausea and stomach ache, that are primarily attributable to the truth that the drug slows down gastric emptying. As meals stays within the abdomen for an extended time period, it will probably result in a sense of nausea or indigestion.” is,” mentioned Dr. Revital Gorodsky Baskin advised Healthline.

“Usually, these negative effects subside or subside inside a couple of months. Most sufferers say they tolerate the negative effects,” she mentioned.

Different widespread negative effects embrace lack of urge for food, belching, bloating, vomiting, diarrhea, and constipation.

Like every drugs that lowers blood sugar, semaglutide may cause low blood sugar episodes.

In uncommon instances, individuals might develop critical negative effects reminiscent of pancreatitis, kidney injury, gallbladder injury or a extreme allergic response. Analysis in rats means that the drug might also improve the danger of thyroid C-cell tumors.

“Semaglutide is contraindicated if an individual has a historical past of pancreatitis in addition to a private or household historical past of medullary thyroid most cancers,” Gorodeski Baskin mentioned.

If a affected person develops negative effects which can be tough to handle, their physician might advocate adjustments to their therapy plan.

Semaglutide is a glucagon-like peptide-1 receptor agonist (GLP-1 RA), a category of drug used to deal with kind 2 diabetes and, in some instances, assist weight administration.

“GLP-1 has been a game-changer within the therapy of RA diabetes and weight problems,” says Dr. Greg Faiman, MD advised Healthline.

The GLP-1 RA mimics GLP-1, a hormone that helps management urge for food and blood sugar. These medicine gradual digestion, improve insulin manufacturing, and scale back the discharge of saved sugar within the liver, which helps scale back urge for food and decrease blood sugar ranges.

A number of varieties of GLP-1 RAs have been developed, with semaglutide being one of many latest choices.

analysis counsel that semaglutide might not solely assist decrease blood sugar and weight however might also scale back the danger of coronary heart illness in individuals with kind 2 diabetes.

In latest studies on social media and within the information, some individuals have described unusual adjustments in how sure meals style or attraction to them when they’re taking semaglutide.

For instance, Insider lately reported on a case the place a girl misplaced her style for espresso, chocolate, floor beef and her favourite fried-chicken sandwich whereas taking the drug.

In a thread on the social media platform Reddit, posters equally described favourite meals that had misplaced their attraction or developed an disagreeable bitter style. “Unexpectedly yesterday, one thing was…off,” wrote one poster.[My favorite french fries] tasted bitter for me. I had by no means tasted them like this earlier than. I could have nearly cried. I like these tasteless issues, and all of a sudden they style like potato-sized items of metallic.

Messer and Gorodsky Baskin each advised Healthline that they’ve obtained comparable studies from a few of their sufferers. Whereas such adjustments could also be distressing or distressing for some sufferers, others might discover it much less bothersome and even useful in managing meals cravings.

“I’ve actually heard that meals is much less pleasant and sometimes does not style the identical,” Messer mentioned. “Nevertheless, the connection with meals inevitably improves as meals turns into much less of an enemy and fewer of a affected person’s head house.”

In distinction, Faiman mentioned he hasn’t heard of any sufferers who’ve developed a change of their sense of style or new meals whereas taking semaglutide. He attributes the change in consuming habits amongst individuals who take the drug to urge for food loss, reasonably than to aversion to style or meals.

“I’ve by no means heard of a grievance of this for a affected person on any kind of semaglutide,” he mentioned. “Most say they’ve a decreased urge for food and can’t eat as a lot as earlier than.”

a quick research 2020 examined meals style amongst individuals taking semaglutide and located no vital distinction in comparison with these taking a placebo.

Some sufferers receiving prescriptions for semaglutide have confronted challenges accessing the drug in latest months attributable to excessive demand and producer shortages.

Each Ozempic and Vigovi have been in brief provide in the USA and different international locations around the globe.

“Particularly attributable to greater than anticipated demand for Ozempic, there [have been] Challenges in getting the drugs,” Faiman mentioned. “These at the moment are resolved for probably the most half. In my sufferers, we had been in a position to give samples of some sufferers. Others had been in a position to get their medicines from the pharmacy however in smaller quantities – month-to-month as a substitute of quarterly.

Gorodeski Baskin advised Healthline that some sufferers have needed to journey to a number of pharmacies to fill their prescriptions for semaglutide. In some instances, they’ve needed to prescribe one other therapy for sufferers who’ve been unable to entry the drug.

“Most often, this has led me to prescribe another GLP-1 agonist – and for the reason that various is not so good as semaglutide, it has led to frustration,” she mentioned.

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